Severe sepsis

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ICD10 Diagnosis
Dx: Severe sepsis
ICD10 code: R65.1
Pre-ICD10 counterpart: Severe Sepsis
Charlson/ALERT Scale: none
APACHE Como Component: none
APACHE Acute Component: 2019-0: Sepsis
Start Date:
Stop Date:
External ICD10 Documentation

This diagnosis is a part of ICD10 collection.

  • SMW
    • 2019-01-01
    • 2999-12-31
    • R65.1
  • Cargo


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  • SMW
  • Cargo


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  • SMW
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Additional Info

  • Even though as of November 2017 ICD-10 has not yet been modified to reflect it, we are using the 2016 consensus definition of sepsis and septic shock (JAMA 315(8):801-10, 2016). These new definitions completely do away with talking about the Systemic Inflammatory Response Syndrome (SIRS). In the 2016 definitions we have just 2 subcategories:
    • Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection -- NOTE this was the 2001 definition of "severe sepsis"
    • Septic shock is a subset of sepsis in which profound circulatory, cellular and metabolic abnormalities are associated with a greater risk of mortality than with sepsis alone
  • For these the cause is proven infection, OR presumed infection -- thus positive cultures are not required.
  • Do not code this if the patient qualifies as having Shock, septic.
  • The 2016 consensus group defined the ORGAN DYSFUNCTION as an acute CHANGE from patient's baseline total SOFA score by 2 or more points -- where the baseline SOFA score can be assumed to be 0 in patients not known to have preexisting organ dysfunction.
  • Here is the SOFA scoring:
Category 0 1 2 3 4
GCS 15 13-14 10-12 6-9 <6
Platelets >=150 <150 <100 <50 <20
Serum bilirubin (uM) <20 20-32 33-101 102-204 >204
Serum creatinine (uM) <110 110-170 171-299 300-440 >440
Urine output (mL/day) <500 <200
PaO2/FIO2 >=400 <400 <300 <200 <100
Cardiovascular MAP>=70 MAP<70 see note A see note B see note C
  • Note A: dopamine < 5 OR any dose of dobutamine
  • Note B: dopamine 5.1-15 OR epi<=0.1 OR norepi<=0.1
  • Note C: dopamine >15 OR epi>0.1 OR norepi>0.1
  • for these all doses are in microgram/kg/min


Alternate ICD10s to consider coding instead or in addition

Candidate Combined ICD10 codes

  • Also code the causative infection.

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