Central Line Associated Blood-Stream Infection (CLA-BSI) rate

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CLA-BSI defined using CDC case definition.

QI domain

  • Safe


CLA-BSIs increase morbidity, mortality and costs. It can be prevented using evidence-based interventions. This measure can be used to detect changes related to implementation or lack of adherence to these best practices.

Sampling Plan / Procedure

    • A central lines (CL) is a central venous catheters (CVC) that terminates at or close to the heart or one of the great vessels. Great vessels include the pulmonary artery, superior vena cava, inferior vena cava, brachiocephalic, internal jugular, subclavian, external iliac and the common femoral veins.
      • Could we link to Central Line for details instead so that if we change any they will remain consistent?
  • SMW

  • Cargo

  • Categories
  • 100% sampling for all cases with CLA-BSI incidence following the criteria listed in CLA-BSI

Inclusion Criteria

CVCs include percutaneous non-tunnelled, tunnelled (e.g. Hickman), peripherally inserted (PICC) and pulmonary artery catheters.

Exclusion Criteria

This does not include totally implanted devices (e.g. Ports), arterial catheters, pacemaker leads and other non-infusion devices.


  • Recording the date the CLA-BSI occurred.
  • Daily recording of dates patients have CL or CVC
  • Total number of Central Line days are calculated and reported on a monthly, quarterly or yearly basis based on the daily data.
  • Time Reference is calendar month, quarter or year.

Definition and Derivation

CLA-BSI per 1000 Central line days.


Number of CLA-BSI incidence during the ICU stay of a reporting period


Total Number of Central Line days at 2300 HR of a reporting period

Data Sources

SAS Program

  • The SAS program to get the CLA_BSI is X:\Julie\SAS_CFE\CFE_macros\Pre_ICD10_AcqDx.sas
  • The SAS program to get the Central Line Days is X:\Julie\SAS_CFE\CFE_macros\CFE_tiss28.sas

Report Users

  • Critical Care Directors, Critical Care Unit Managers and WRHA Outcome Improvement Team Committee
  • St Boniface Cardiac Sciences Program (STB site only)
  • HSC Infection Prevention & Control (HSC site only)
  • WRHA Infection Prevention & Control

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