Drug or biological substance/agent NOS, adverse effect

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ICD10 Diagnosis
Dx: Drug or biological substance/agent NOS, adverse effect
ICD10 code: Y57.8
Pre-ICD10 counterpart: Allergic reaction
Charlson/ALERT Scale: none
APACHE Como Component: none
APACHE Acute Component: none
Start Date: 2017-09-18
External ICD10 Documentation
This diagnosis is a part of ICD10 collection.

Additional Info

Includes:

  • X-ray contrast dye
  • drug fever
  • drug interactions


Adverse effect codes

  • This information pertains to the following codes:
Adverse effect codes:
  • It refers to pharmaceuticals and other biological substances
  • Do not confuse this group of codes with Template:ICD10 Guideline overdose or Template:ICD10 Guideline poisoning by non-pharmaceuticals
  • The definition of this category requires that both of the following be true: (1) something bad happened as a direct result of the agent AND (2) the agent was used with an appropriate dosing regimen.
    • The “something bad” can be a threat to life/limb/organ function -- but what distinguishes this category from Category:Overdose is whether the dose/dosing regimen was appropriate or not.
  • These adverse effects are almost all immune-mediated and include: allergic reactions, hypersensitivity reactions, more vaguely defined “adverse drug reactions”
  • In addition to a number of codes for specific agents (e.g. insulin), or classes of agents (e.g. beta-blockers) there are several levels of “wastebasket” codes -- the final, all-encompassing wastebasket here is Drug or biological substance/agent NOS, adverse effect
  • For bad outcomes caused by overdoses, in most cases a counterpart dx will exits in:
Overdose codes:

Coding substance related ICD10 diagnoses

See ICD10 Guideline for drugs and substances for more info on coding substance related ICD10 diagnoses.

Alternate ICD10s to consider coding instead or in addition

Adverse effect codes:
Overdose codes:

Candidate Combined ICD10 codes

Related CCI Codes

Data Integrity Checks (SMW)

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  • Had code T88.7 when we first started but was later changed to this code. I have deleted the original code from the tables, but it might still linger in other references. Once you are sure you don't need this info, please delete the comment. Since this would only exist in test data we don't need to keep it long-term.
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