View source for Hemolytic-uremic syndrome (HUS)

{{ICD10 transition status
| OldDxArticle =Hemolytic Uremic Syndrome
| CurrentStatus = reconciled
| InitialEditorAssigned = Elaine Nagy
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| ICD10 Code=D59.3
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{{ICD10 category|Renal/urinary}}{{ICD10 category|Heme/immunology}}{{ICD10 category|Anemia}} 

== Additional Info ==
Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized by a triad of hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia). It predominantly, but not exclusively, affects children. Most cases are preceded by an episode of infectious, sometimes bloody, diarrhea acquired as a foodborne illness or from a contaminated water supply caused by E. coli O157:H7, other non-O157:H7 E. coli serotypes, Shigella, and Campylobacter. A variety of viruses have also been implicated as a causative agent. It is now the most common cause of acquired acute renal failure in childhood. It is a medical emergency and carries a 5–10% mortality rate; of the remainder, the majority recover without major consequences, approximately 30% suffer residual renal injury. The primary target appears to be the vascular endothelial cell. This may explain the pathogenesis of HUS, in which a characteristic renal lesion is capillary microangiopathy.[1]

== Alternate ICD10s to consider coding instead or in addition ==
* Other Anemias ([[:Category:Anemia]])
*[[Hemoglobinuria]]
Consider infectious cause.

== Candidate [[Combined ICD10 codes]] ==

== Related CCI Codes ==

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== Related Articles ==
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