Monoclonal gammopathy of undetermined significance (MGUS): Difference between revisions

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+{{ICD10 category|Heme/immunology}}{{ICD10 category|Neoplastic}}
-{{ICD10 category|Heme/immunology}}{{ICD10 category|Neoplastic}}
 == Additional Info ==
+Monoclonal gammopathy of undetermined significance (MGUS, unknown or uncertain may be substituted for undetermined), formerly benign monoclonal gammopathy, is a condition in which an abnormal immunoglobin protein (known as a paraprotein) is found in the blood during standard laboratory blood tests. MGUS resembles multiple myeloma and similar diseases, but the levels of antibody are lower,[2] the number of plasma cells (white blood cells that secrete antibodies) in the bone marrow is lower, and it has no symptoms or major problems. However, multiple myeloma develops at the rate of about 1.5% a year, so doctors recommend monitoring it yearly.
+The progression from MGUS to multiple myeloma usually involves several steps. In rare cases, it may also be related with a slowly progressive symmetric distal sensorimotor neuropathy.[3]
+Not to be confused with Monoclonal gammopathy.
+'''Includes'''
+*IgA Lambda Monoclonal Gammopathy
+* POEMS syndrome (Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes)    [[https://www.mayoclinic.org/diseases-conditions/poems-syndrome/symptoms-causes/syc-20352678]] also known as Crow-Fukase syndrome, Osterosclerotic myeloma.  combine with manifestations eg. [[Peripheral neuropathy or polyneuropathy, NOS]], [[Hepatomegaly]], [[Lymphadenopathy, NOS]] etc.
-== Alternate ICD10s to consider coding instead ==
-(turn these into links to the actual diagnosis articles if possible. For some that might make no sense.)
+{{ICD10 Guideline Cancer}}
+== Alternate ICD10s to consider coding instead or in addition ==
+*[[Multiple myeloma]]
 == Candidate [[Combined ICD10 codes]] ==
-(put links to likely candidates coded with this one, eg. a cause for a trauma.)
+== Related CCI Codes ==
+{{Data Integrity Check List}}
 == Related Articles ==
 {{Related Articles}}
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