Edit ICD10 dx: Acute promyelocytic leukaemia (APL)

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{{ICD10 transition status | OldDxArticle = | CurrentStatus = reconciled | InitialEditorAssigned = Debbie Page-Newton }} == Additional Info == *Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. *In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARα or RARA) gene and is distinguished from other forms of AML by its responsiveness to all-trans retinoic acid (ATRA; also known as tretinoin) therapy. *Acute promyelocytic leukemia was first characterized in 1957 by French and Norwegian physicians as a hyperacute fatal illness, with a median survival time of less than a week. Today, prognoses have drastically improved; 10-year survival rates are estimated to be approximately 77% according to one study {{ICD10 Guideline leukemia vs lymphoma}} {{ICD10 Guideline Cancer}} == Alternate ICD10s to consider coding instead or in addition == {{ListICD10Category | categoryName = Leukemia}} == Candidate [[Combined ICD10 codes]] == == Related CCI Codes == {{Data Integrity Check List}} == Related Articles == {{Related Articles}} {{ICD10 footer}} {{EndPlaceHolder}}

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Edit ICD10 dx: Acute promyelocytic leukaemia (APL)

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