ICD10 Guideline for drugs and substances

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This page contains an ICD10 Coding Guideline for ICD10 collection. See ICD10 coding guidelines for similar pages.

Coding in ICD10 of Issues Related to Drugs and Substances

There are 6 categories of ICD10 codes related to drugs/biologics/agents/substances -- they are DISTINCT and it’s important to distinguish between them.

  • While many of the specific drugs or agents or substances have codes that fall under multiple of the categories (e.g. opioids), there is not perfect symmetry, i.e. there may be an individual code for a given agent in one category, while for another category that agent may instead go into a wastebasket code. Benzodiazepines are one such example.
  • Distinguishing between: Sedative/hypnotics, Hallucinogens, and Psychoactive substance NOS
  • you wrote "--- TINA the following goes in the 15 specific pages only." - what do you mean by that? I think this page might have got lost, it might have been addressed otherwise.
  • AG REPLY --- I meant that distinguishing between these 3 categories of agents really only needs to be listed in codes that represent those categories, which specifically are: F13.0, F13.2, F13.3, F19.0, F19.2, F19.3, F16.0, F16.2, F16.3, T40.9 and Y49.6)
  • SMW


  • Cargo


  • Categories
    • It’s usually relatively easy to distinguish them, but not always
    • Sedative/hypnotics -- includes benzodiazepines; barbiturates; dilantin and most other antiseizure drugs; tricyclics and most anti-depressants (but not lithium, which is categorized under “Psychiatric drug NOS”
    • Hallucinogens -- includes LSD, mescaline, ketamine, cannabis
    • Psychoactive or psychiatric substances NOS
      • pharmaceuticals: includes lithium, phenothiazines, olanzapine, respiradone (Respirdol), olanzapine (Zyprexa), quetiapine (Seroquel), other antipsychotics, methylphenidate(Ritalin), amphetamines (Adderol)
      • street drugs/agents: includes ecstacy (MDMA), nitrous oxide