Acute megakaryoblastic leukemia

ICD10 Diagnosis
Dx:	Acute megakaryoblastic leukemia
ICD10 code:	C94.2
Pre-ICD10 counterpart:	none assigned
Charlson/ALERT Scale:	Any malignancy, including lymphoma and leukemia, except of skin
APACHE Como Component:	Immunocompromised
APACHE Acute Component:	none
Start Date:
Stop Date:
External ICD10 Documentation	ICD-10 CM Wikipedia ICD-10 Wikipedia WHO ICD10 documentation ICD10data.com

This diagnosis is a part of ICD10 collection.

• SMW
  • 2019-01-01
  • 2999-12-31
  • C94.2

• Cargo

• Categories

• SMW

• Cargo

• Categories

• SMW

• Cargo

• Categories

Additional Info

• Acute megakaryoblastic leukemia (AMKL) is a form of leukemia where a majority of the blasts are megakaryoblastic.

• It is classified under AML-M7 category of the French-American-British classification.

• The latest WHO classification (2008, Lyon), classifies Acute Myeloid Leukemia into distinct subtypes, based on clinico-pathological and molecular features. Acute megakaryoblastic leukemia is placed under the AML-Not Otherwise Specified subcategory.

• Diagnosis requires more than 20% Blasts in the marrow/ peripheral blood with more than 50% demonstrating megakaryocytic derivation by morphology, immunophenotypic or electron microscopic studies.

CAUSES: It is associated with GATA1, and risks are increased in individuals with Down syndrome. However, not all cases are associated with Down syndrome, and other genes can also be associated with AMKL. Another related gene is MKL1, which is also known as "MAL".[6] This gene is a cofactor of serum response factor.

Alternate ICD10s to consider coding instead or in addition

Acute myeloid leukemia (AML)

Candidate Combined ICD10 codes

(put links to likely candidates coded with this one, eg. a cause for a trauma.)

Related Articles

Skin	Trauma Abdominal trauma Burn Chemical burn Fracture Head trauma Head trauma (old) Joint/ligament trauma Lower limb trauma Muscles/tendon trauma Neck trauma Potential trauma Thoracic trauma Traumatic Amputation Traumatic fracture Upper limb trauma Vascular trauma	Renal/urinary Chronic kidney disease Nephritic syndrome Renal failure Renal/Urinary neoplasm Urinary tract infection	Infectious disease Antibiotic resistance Bacteria COVID Double duty pathogen Encephalitis Fungus Iatrogenic infection Infection requiring pathogen Infection with implied pathogen Influenza Intra-abdominal infection Lower respiratory tract infection Meningitis Non-specific pathogens Osteomyelitis Pathogens Pneumonia Potential infection Tuberculosis Upper respiratory tract infection Virus
ENT	Testing Imaging	Cardiovascular Aneurysm Aortic Aneurysm Arrhythmia Arterial thromboembolism Atherosclerosis Cardiac septum problem Cerebral Hemorrhage/Stroke Heart valve disease Hemorrhage Hypertension Hypotension Ischemia Ischemic gut Ischemic heart disease Myocardial Infarction Pulmonary embolism Pulmonary hypertension Vasculitis Venous thromboembolism	Hereditary/congenital
Eye	Mechanism Transportation mechanism	Neoplastic Benign neoplasm Endocrine neoplasm Female genital neoplasm Gastrointestinal neoplasm Heme/immunology neoplasm Leukemia Lymphoma Male genital neoplasm Metastasis Musculoskeletal/soft tissue neoplasm Neuro neoplasm Primary malignancy Renal/Urinary neoplasm Respiratory neoplasm Skin neoplasm	Heme/immunology Allergy Anemia Heme/immunology neoplasm Hemophilia Leukemia Thrombocytopenia
Misc Adverse effect Alcohol related Allergy Anesthetic related Antidepressant related Awaiting/delayed transfer COVID Cannabis related Cocaine related Decubitus ulcer Diagnosis implying death Exposure Fistula Hallucinogen related Has one Healthcare contact Hemorrhage Iatrogenic Metabolic/nutrition Non-traumatic fracture Observation Organ removal Ostomy Overdose Paralysis Past medical history Poisoning Psychoactive substance NOS related Radiation related Retired Code Rheumatic disease Sedative related Shock Solvent related Spine Stimulant related Transplant	Reproductive Abortion Breast disease Female genital neoplasm Male genital neoplasm Peripartum	Gastrointestinal Cirrhosis GI ulcer Gastroenteritis Gastrointestinal neoplasm Hepatitis Hernia Inflammatory Bowel Disease Intra-abdominal infection Ischemic gut Liver disease Liver failure Pancreas disease Pancreatitis Peptic ulcer	Musculoskeletal/soft tissue Hernia Joint/ligament trauma Muscle problem Muscles/tendon trauma Musculoskeletal/soft tissue neoplasm Osteomyelitis
Psych Addiction Antidepressant related Delirium Dementia Hallucinogen related Opioid related Psychoactive substance NOS related Sedative related Solvent related Stimulant related Withdrawal	Respiratory Asthma Influenza Inhalation Lower respiratory tract infection Pleural abnormalities Pneumoconiosis Pneumonia Pneumothorax Pulmonary embolism Respiratory neoplasm Sleep disorder Tracheostomy Upper respiratory tract infection	Poisoning Acute intoxication Addiction Opioid related Overdose Poisoning by non-pharmaceuticals Stimulant related Withdrawal
Neuro Cerebral Hemorrhage/Stroke Encephalitis Encephalopathy Meningitis Neuro neoplasm Paralysis	Symptom/Sign Pain	Endocrine disorder Adrenal Insufficiency Diabetes Endocrine neoplasm Metabolic/nutrition

Show all ICD10 Subcategories

ICD10 Categories: ANCA-associated Vasculitis (AAV), Abdominal trauma, Abortion, Acute intoxication, Addiction, Adrenal Insufficiency, Adverse effect, Alcohol related, Allergy, Anemia, Anesthetic related, Aneurysm, Antibiotic resistance, Antidepressant related, Aortic Aneurysm, Arrhythmia, Arterial thromboembolism, Asthma, Atherosclerosis, Awaiting/delayed transfer, Bacteria, Benign neoplasm, Breast disease, Burn, COVID, Cannabis related, Cardiac septum problem, Cardiovascular, Cerebral Hemorrhage/Stroke, Chemical burn, Chronic kidney disease, Cirrhosis, Cocaine related, Decubitus ulcer, Delirium, Dementia, Diabetes, Diagnosis implying death, Double duty pathogen, ENT, Encephalitis, Encephalopathy, Endocrine disorder, Endocrine neoplasm, Exposure, Eye, Female genital neoplasm, Fistula, Fracture, Fungus, GI ulcer, Gastroenteritis, Gastrointestinal, Gastrointestinal neoplasm, Hallucinogen related, Has one, Head trauma, Head trauma (old), Healthcare contact, Heart valve disease, Heme/immunology, Heme/immunology neoplasm, Hemophilia, Hemorrhage, Hepatitis, Hereditary/congenital, Hernia, Hypertension, Hypotension, Iatrogenic, Iatrogenic infection, Iatrogenic mechanism, Imaging, Infection requiring pathogen, Infection with implied pathogen, Infectious disease, Inflammatory Bowel Disease, Influenza, Inhalation, Intra-abdominal infection, Ischemia, Ischemic gut, Ischemic heart disease, Joint/ligament trauma, Leukemia, Liver disease, Liver failure, Lower limb trauma, Lower respiratory tract infection, Lymphoma, Male genital neoplasm, Mechanism, Meningitis, Metabolic/nutrition, Metastasis, Misc, Muscle problem, Muscles/tendon trauma, Musculoskeletal/soft tissue, Musculoskeletal/soft tissue neoplasm... further results