Acquired deficiency of clotting factors
ICD10 Diagnosis | |
Dx: | Acquired deficiency of clotting factors |
ICD10 code: | D68.4 |
Pre-ICD10 counterpart: | Transfusion Coagulopathy |
Charlson/ALERT Scale: | none |
APACHE Como Component: | none |
APACHE Acute Component: | none |
Start Date: | |
Stop Date: | |
External ICD10 Documentation |
This diagnosis is a part of ICD10 collection.
Additional Info
- Coagulation disorders in liver disease: The liver plays a central role in the clotting process, and acute and chronic liver diseases are invariably associated with coagulation disorders due to multiple causes: decreased synthesis of clotting and inhibitor factors, decreased clearance of activated factors, quantitative and qualitative platelet defects, hyperfibrinolysis, and accelerated intravascular coagulation.
- Vitamen K deficiency: Combined deficiency of vitamin K-dependent clotting factors II, VII, IX and X (and proteins C, S, and Z) is usually an acquired clinical problem, often resulting from liver disease, malabsorption, or warfarin overdose.
- Transfusion and dilutional coagulopathy:A massive transfusion of red blood cells (RBCs) may lead to a dilutional coagulopathy, as plasma-reduced RBCs contain neither coagulation factors nor platelets. Secondly, haemorrhage, as a consequence of delayed or inadequate perfusion, can result in disseminated intravascular coagulation. This causes consumption of platelets and coagulation factors and may account for the numerical distortion of clotting studies appearing out of proportion to the volume of blood transfused. Aggressive, expectant replacement of clotting factors with fresh frozen plasma (FFP), platelets and cryoprecipitate transfusions are required to prevent this coagulopathy becoming severe enough to make haemorrhage worse.
Alternate ICD10s to consider coding instead or in addition
Candidate Combined ICD10 codes
(put links to likely candidates coded with this one, eg. a cause for a trauma.)
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