Hypergammaglobulinemia

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ICD10 Diagnosis
Dx: Hypergammaglobulinemia
ICD10 code: D89.2
Pre-ICD10 counterpart: none assigned
Charlson/ALERT Scale: none
APACHE Como Component: none
APACHE Acute Component: none
Start Date: 2018-11-25
Stop Date:
External ICD10 Documentation

This diagnosis is a part of ICD10 collection.

  • SMW
    • 2018-11-25
    • 2999-12-31
    • D89.2
  • Cargo


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Hypergammaglobulinemia is a rare disorder affecting the immune system of the body. It is a condition in which the immune system behaves abnormally to produce increased amount of gamma globulins, a special type of antibodies. Gamma globulins (antibodies) are type of proteins present only in blood.

In hypergammaglobulinemia, an excess amount of antibodies circulate in blood. Among many types of gamma globulin, immunoglobulins are the ones which are checked for diagnosing hypergammaglobulinemia. Patient suffering from this disorder may have enlarged lymph nodes, liver and spleen. They have poor immunity and are prone to opportunistic infections.

Diseases such as HIV, myeloma, hepatitis C, cirrhosis of liver attack the immune system which may result into hypergammaglobulinemia. Treatment consists of immunoglobulin IgG replacement therapy where IgG antibodies are injected for improving immunity and fight infections.

Alternate ICD10s to consider coding instead or in addition

Candidate Combined ICD10 codes

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