Progressive Multifocal Leukoencephalopathy (PML): Difference between revisions

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{{ICD10 dx
|ICD10 Code=A81.2
}}
{{ICD10 category|Infectious disease}}
{{ICD10 category|Neuro}}
{{ICD10 category|Virus}}
{{ICD10 category|Potential infection}}
{{ICD10 transition status
{{ICD10 transition status
| OldDxArticle =Neurologic Other
| OldDxArticle =Neurologic Other
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| InitialEditorAssigned = Allyson Alcudia
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{{ICD10 dx
 
| MinimumCombinedCodes =
 
| ICD10 Code=A81.2
| BugRequired= 
}}
{{ICD10 category|Infectious disease}}{{ICD10 category|Infection with implied pathogen}}{{ICD10 category|Neuro}}


== Additional Info ==
== Additional Info ==
 
*PML is a rare and often fatal neurologic disease marked by progressive, immune-mediated, multifocal damage to the white matter of the brain.
* also known as vanishing white matter disease (VWM)
*Most cases are caused by JC virus, however, an increasing other cause is new immune-modifying drugs.


== Alternate ICD10s to consider coding instead or in addition ==
== Alternate ICD10s to consider coding instead or in addition ==


== Candidate [[Combined ICD10 codes]] ==
== Candidate [[Combined ICD10 codes]] ==
{{ICD10 Guideline Infection}}


== Related CCI Codes ==


== Related  CCI Codes ==
{{Data Integrity Check List}}


== Related Articles ==
== Related Articles ==
{{Related Articles}}
{{Related Articles}}


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{{ICD10 footer}}
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Latest revision as of 13:18, 19 August 2025

ICD10 Diagnosis
Dx: Progressive Multifocal Leukoencephalopathy (PML)
ICD10 code: A81.2
Pre-ICD10 counterpart: none assigned
Charlson/ALERT Scale: none
APACHE Como Component: none
APACHE Acute Component: none
Start Date:
Stop Date:
Data Dependencies(Reports/Indicators/Data Elements): No results
External ICD10 Documentation

This diagnosis is a part of ICD10 collection.

  • SMW
    • 2019-01-01
    • 2999-12-31
    • A81.2
  • Cargo


  • Categories
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Additional Info

  • PML is a rare and often fatal neurologic disease marked by progressive, immune-mediated, multifocal damage to the white matter of the brain.
  • also known as vanishing white matter disease (VWM)
  • Most cases are caused by JC virus, however, an increasing other cause is new immune-modifying drugs.

Alternate ICD10s to consider coding instead or in addition

Infections

Infections in ICD10 have combined coding requirements for some of their pathogens. Any that have antibiotic resistances would store those as Combined ICD10 codes as well. If the infection is acquired in the hospital, see Nosocomial infection, NOS. See Lab and culture reports for confirmation and details about tests. See Infections in ICD10 for more general info.

Possible Simultaneous Presence of Multiple Different Types of Infection in a Single Site

  • This refers to the situation where there may be simultaneous infection with multiple types of organisms -- e.g. 2 of bacteria, virus, fungus. While a classic example is a proven viral pneumonia (e.g. influenza) with a suspected/possible bacterial pneumonia superimposed, this kind of thing can occur in places other than the lungs, e.g. meningitis.
    • The "signature" of this is typically the patient being treated simultaneously with antimicrobial agents for multiple types of organisms. BUT don't confuse this with there being infections at DIFFERENT body sites.
  • As per our usual practice, we will consider a diagnosis as present if the clinical team thinks it's present and are treating it, with the exception that the team initially treated for the possible 2nd type of infection but then decided it likely was NOT present and stopped those agents.
  • And remember that Infectious organism, unknown is used when the the specific organism is unknown (this could be not knowing the TYPE of organism, or suspecting the type but not having identified the specific organism of that type), while when the organism has been identified but it's not in our bug list, THEN use Bacteria, NOS, Virus, NOS or Fungus or yeast, NOS.

Attribution of infections

See Attribution of infections


Data Integrity Checks (automatic list)

none found

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