Acute myeloid leukemia (AML)
ICD10 Diagnosis | |
Dx: | Acute myeloid leukemia (AML) |
ICD10 code: | C92.0 |
Pre-ICD10 counterpart: | AML |
Charlson/ALERT Scale: | Any malignancy, including lymphoma and leukemia, except of skin |
APACHE Como Component: | Immunocompromised |
APACHE Acute Component: | none |
Start Date: | |
Stop Date: | |
External ICD10 Documentation |
This diagnosis is a part of ICD10 collection.
Additional Info
- Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal white blood cells that build up in the bone marrow and interfere with the production of normal blood cells. AML is the most common acute leukemia affecting adults, and its incidence increases with age. AML is a relatively rare disease, accounting for roughly 1.2% of cancer deaths in the United States, or 3.7 persons per 100,000 of the population.
- The symptoms of AML are caused by replacement of normal bone marrow with leukemic cells, which causes a drop in red blood cells, platelets, and normal white blood cells. These symptoms include fatigue, shortness of breath, easy bruising and bleeding, and increased risk of infection. Several risk factors and chromosomal abnormalities have been identified, but the specific cause is not clear. As an acute leukemia, AML progresses rapidly and is typically fatal within weeks or months if left untreated.
- AML has several subtypes; treatment and prognosis vary among subtypes. AML is cured in 35–40% of people under 60 years old and 5–15% over 60 years old. Older people who are not able to withstand intensive chemotherapy have an average survival of 5–10 months
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