Psychoactive substance NOS, chronic abuse/dependence/addiction

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ICD10 Diagnosis
Dx: Psychoactive substance NOS, chronic abuse/dependence/addiction
ICD10 code: F19.2
Pre-ICD10 counterpart: Chronic Drug Abuse
Charlson/ALERT Scale: none
APACHE Como Component: none
APACHE Acute Component: none
Start Date:
Stop Date:
External ICD10 Documentation

This diagnosis is a part of ICD10 collection.

  • SMW
    • 2019-01-01
    • 2999-12-31
    • F19.2
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Additional Info

  • Use this code if no specific addiction code is available/or if substance is unknown.

Common Psychoactive Substances

  • Pharmaceuticals:
    • lithium
    • phenothiazines
    • olanzapine (Zyprexa)
    • respiradone (Respirdol
    • quetiapine (Seroquel)
    • methylphenidate(Ritalin)
    • amphetamines (Adderol)
    • other antipsychotics
  • Street drugs/agents:
    • ecstacy (MDMA), also referred to as Molly
    • nitrous oxide

Coding substance related ICD10 diagnoses

See ICD10 Guideline for drugs and substances for more info on coding substance related ICD10 diagnoses.

Chronic Substance Abuse Guidelines

  • This category indicates, as stated, that the patient has, for the indicated substance, chronic abuse and/or dependency/addiction
  • Chronic abuse/dependence/addiction does not necessarily mean there is current acute intoxication or withdrawal
  • This is almost always going to be a Comorbid Diagnosis --- and it is a comorbid even if it is being treated in the hospital. For example continuing to get methadone for chronic heroin abuse in hospital is no different than continuing to get an antihypertensive in hospital for hypertension; in both cases the chronic condition is correctly coded as a comorbid.
    • It is very rare (but not impossible) for a patient to become dependent or addicted as an Acquired Diagnoses -- most of these occur in long-stay patients who are getting narcotics for pain and become habituated or addicted, e.g. postoperatively.
    • This is different from when a patient with chronic abuse/addiction isn't recognized to have that until after admission -- THIS is not a acquired diagnosis and should be correctly listed as a Comorbid Diagnosis
  • When a patient with a chronic abuse/addiction is admitted and that chronic abuse/addiction is part of the reason for hospital admission (e.g. for inpatient care of addiction), then that diagnosis should be listed as both a Comorbid Diagnosis and also an Admit Diagnosis
  • The issue of "chronic abuse/dependence/addiction" is hard to pin down and comes down to a judgment call (specifically, the judgment of collectors and the physicians writing chart notes):
  • Obviously it is present if CURRENT dependence or addiction is present.
  • But it can exist even in the absence of identified dependence or addiction, if chronic abuse is present.
  • There are actually TWO judgments required to identify chronic abuse: (a) what is heavy use, and (b) what duration qualifies as chronic use
    • Furthermore, and complicating the issue, is that chronic abuse is about BOTH duration and quantity.
    • Heavier use for shorter periods COULD be considered as chronic abuse.
    • e.g. even without dependence or addiction, >5 years of heavy or regular use qualifies as "chronic abuse"
    • But the actual CUTOFF for the duration that qualifies as "chronic" is not easily delineated and depends somewhat on how heavy the use is
      • So again, the bottom line for defining "chronic abuse" is a judgment call

Do not code for past drug use

Do NOT include the chronic abuse/dependence/addiction code if the person is no longer using, but DO code any resulting long-term problem, e.g. liver cirrhosis as a result of past alcohol abuse, or ischemic heart disease as a result past cocaine abuse.

Distinguishing between Sedative/hypnotics, Hallucinogens, and Psychoactive substances

Common sedatives or hypnotics

  • benzodiazepines
  • barbiturates
  • dilantin and most other antiseizure drugs
  • tricyclics and most anti-depressants (but not lithium, which is categorized under “Psychiatric drug NOS”)
  • xylazine is a non-opiate sedative, analgesic and muscle relaxant authorized for veterinary use in the US, now being found in a number of illicit drug mixtures such as fentanyl, cocaine and heroin

Common hallucinogens

  • LSD (lysergic acid diethylamide)
  • PCP (phencyclidine)
  • magic mushrooms (psilocybin)
  • ketamine
  • mescaline (peyote cactus)
  • morning glory seeds
  • datura
  • don't include cannabis under general hallucinogens, see

Common Psychoactive Substances

  • Pharmaceuticals:
    • lithium
    • phenothiazines
    • olanzapine (Zyprexa)
    • respiradone (Respirdol
    • quetiapine (Seroquel)
    • methylphenidate(Ritalin)
    • amphetamines (Adderol)
    • other antipsychotics
  • Street drugs/agents:
    • ecstacy (MDMA), also referred to as Molly
    • nitrous oxide

Alternate ICD10s to consider coding instead or in addition

Addiction codes:
psychoactive substance NOS related codes:
Alcohol related codes:
opioid related codes:
sedative related codes:
cocaine related codes:
Hallucinogen related codes:
solvent related codes:

Candidate Combined ICD10 codes

Related CCI Codes

Data Integrity Checks (automatic list)

none found

Related Articles

Related articles:


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