Psychoactive substance NOS, acute intoxication

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ICD10 Diagnosis
Dx: Psychoactive substance NOS, acute intoxication
ICD10 code: F19.0
Pre-ICD10 counterpart: Sedatives/Antidepressants, Cocaine OD, Other overdose, Etoh OD/Intoxication
Charlson/ALERT Scale: none
APACHE Como Component: none
APACHE Acute Component: 2019-0: Drug OD
Start Date:
Stop Date:
External ICD10 Documentation

This diagnosis is a part of ICD10 collection.

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    • 2019-01-01
    • 2999-12-31
    • F19.0
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Additional Info

  • Common Psychoactive Substances:
    • Pharmaceuticals:
      • lithium
      • phenothiazines
      • olanzapine (Zyprexa)
      • respiradone (Respirdol
      • quetiapine (Seroquel)
      • methylphenidate(Ritalin)
      • amphetamines (Adderol)
      • other antipsychotics
    • Street drugs/agents:
      • ecstacy (MDMA)
      • nitrous oxide

Acute intoxication codes

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  • This category simply indicates that the patient was intoxicated -- i.e. drunk, high, etc
  • Acute intoxication does not necessarily mean there is a chronic abuse/dependence/addiction
    • If there was a threat to life, or limb, or to functioning for one or more organs -- then you should instead use, as appropriate, a code from
Overdose codes:
Acute intoxication codes:
Acute intoxication codes:

For situations where patients have overdosed, ie where there is an immediate risk to their life, use the corresponding "overdose" code:

Overdose codes:

Coding substance related ICD10 diagnoses

See ICD10 Guideline for drugs and substances for more info on coding substance related ICD10 diagnoses.

Distinguishing between Sedative/hypnotics, Hallucinogens, and Psychoactive substances

Common sedatives or hypnotics

  • benzodiazepines
  • barbiturates
  • dilantin and most other antiseizure drugs
  • tricyclics and most anti-depressants (but not lithium, which is categorized under “Psychiatric drug NOS”)
  • xylazine is a non-opiate sedative, analgesic and muscle relaxant authorized for veterinary use in the US, now being found in a number of illicit drug mixtures such as fentanyl, cocaine and heroin

Common hallucinogens

  • LSD (lysergic acid diethylamide)
  • PCP (phencyclidine)
  • magic mushrooms (psilocybin)
  • ketamine
  • mescaline (peyote cactus)
  • morning glory seeds
  • datura
  • don't include cannabis under general hallucinogens, see

Common Psychoactive Substances

  • Pharmaceuticals:
    • lithium
    • phenothiazines
    • olanzapine (Zyprexa)
    • respiradone (Respirdol
    • quetiapine (Seroquel)
    • methylphenidate(Ritalin)
    • amphetamines (Adderol)
    • other antipsychotics
  • Street drugs/agents:
    • ecstacy (MDMA), also referred to as Molly
    • nitrous oxide

Alternate ICD10s to consider coding instead or in addition

psychoactive substance NOS related codes:
Acute intoxication codes:
Alcohol related codes:
opioid related codes:
sedative related codes:
cocaine related codes:
Hallucinogen related codes:
solvent related codes:

Candidate Combined ICD10 codes

Related CCI Codes

Data Integrity Checks (automatic list)

none found

Related Articles

Related articles:


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