Antineoplastic/chemotherapy or immunosuppressive drugs, adverse effect

ICD10 Diagnosis
Dx:	Antineoplastic/chemotherapy or immunosuppressive drugs, adverse effect
ICD10 code:	Y43.3
Pre-ICD10 counterpart:	Pancytopenia
Charlson/ALERT Scale:	none
APACHE Como Component:	none
APACHE Acute Component:	none
Start Date:
Stop Date:
External ICD10 Documentation	ICD-10 CM Wikipedia ICD-10 Wikipedia WHO ICD10 documentation ICD10data.com

This diagnosis is a part of ICD10 collection.

• SMW
  • 2019-01-01
  • 2999-12-31
  • Y43.3

• Cargo

• Categories

• SMW

• Cargo

• Categories

• SMW

• Cargo

• Categories

• SMW

• Cargo

• Categories

• SMW

• Cargo

• Categories

Additional Info

Includes:

• Antirejection drugs
• Side effects such as nausea/vomiting
• Differentiation syndrome- Differentiation syndrome is a group of severe reactions to drugs used to treat acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL), both of which are a type of leukemia, or blood cancer. If it is thought to be in part because of an immune system disorder, link that with it.

List of immunosuppressive drugs

Used to treat an increasing variety of conditions: immune-mediated (RA, UC, Crohn's, lupus, MS, psoriasis, etc); after organ transplant. Only considered immunosuppressive if given systemically (po, im or iv) Corticosteroids (unlike all the others, these only count if > a given daily dose and used for at least 2 weeks prior to admission) Dexamethasone: >0.25 mg/day Hydrocortisone: >40 mg/day Prednisone (methyl-prednisolone): >10 mg/day Prednisolone: >8 mg/day Cancer chemotherapy -- includes any agents, if received within the past 6 months Nonsteroidal immunosuppressives -- includes any of these, if received within the past 1 month Abatacept (Orencia) Azathioprine (Imuran) Adalimumab (Humira) Anakinra (Kineret) Basiliximab (Simulect) Certolizumab (Cimzia) Cyclophosphamide (Cytoxan) Cyclosporine Daclizumab (Zinbryta) Etanercept (Enbrel) Everolimus (Afinitor, Zortress) Golimumag (Simponi) Infliximab (Remicade) Ixekizumab (Taltz) Leflunomide (Arava) Lenalidomide Methotrexate Mycophenolate (CellCept) Natalizumab (Tysabri) Rituximab (Rituxan) Secukinumab (Cosentyx) Sirolimus (Rapasumne) Tacrolimus (Prograf) Tocilizumab (Actemra) Tofacitinib (Xeljanz) Ustekinumab (Stelara) Vedolizumab (Entyvio) Do not include hydroxychloroquine - as per task meeting 2022-04-20 it is an immune modulator, but not very immunosuppressive

Adverse effect codes

• SMW

• Cargo

• Categories

• SMW

• Cargo

• Categories

• This information pertains to the following codes:

• It refers to pharmaceuticals and other biological substances
• Do not confuse this group of codes with Template:ICD10 Guideline overdose or Template:ICD10 Guideline poisoning by non-pharmaceuticals
• The definition of this category requires that both of the following be true: (1) something bad happened as a direct result of the agent AND (2) the agent was used with an appropriate dosing regimen.
  • The “something bad” can be a threat to life/limb/organ function -- but what distinguishes this category from Category:Overdose is whether the dose/dosing regimen was appropriate or not.
• These adverse effects are almost all immune-mediated and include: allergic reactions, hypersensitivity reactions, more vaguely defined “adverse drug reactions”
  • examples: drug rash; anaphylactic reaction; drug fever
  • exception: bleeding on coumadin at an appropriate dose is NOT coded here, but as Hemorrhage, due to anticoagulant or thrombolytic drug
• In addition to a number of codes for specific agents (e.g. insulin), or classes of agents (e.g. beta-blockers) there are several levels of “wastebasket” codes -- the final, all-encompassing wastebasket here is Drug or biological substance/agent NOS, adverse effect
• For bad outcomes caused by overdoses, in most cases a counterpart dx will exits in:

Coding substance related ICD10 diagnoses

See ICD10 Guideline for drugs and substances for more info on coding substance related ICD10 diagnoses.

Alternate ICD10s to consider coding instead or in addition

• Tumor lysis syndrome
• Anaphylactic reaction (anaphylaxis)

Candidate Combined ICD10 codes

Related CCI Codes

Data Integrity Checks (automatic list)

none found

Related Articles

Skin	Trauma Abdominal trauma Burn Chemical burn Fracture Head trauma Head trauma (old) Joint/ligament trauma Lower limb trauma Muscles/tendon trauma Neck trauma Potential trauma Thoracic trauma Traumatic Amputation Traumatic fracture Upper limb trauma Vascular trauma	Renal/urinary Chronic kidney disease Nephritic syndrome Renal failure Renal/Urinary neoplasm Urinary tract infection	Infectious disease Antibiotic resistance Bacteria COVID Double duty pathogen Encephalitis Fungus Iatrogenic infection Infection requiring pathogen Infection with implied pathogen Influenza Intra-abdominal infection Lower respiratory tract infection Meningitis Non-specific pathogens Osteomyelitis Pathogens Pneumonia Potential infection Tuberculosis Upper respiratory tract infection Virus
ENT	Testing Imaging	Cardiovascular Aneurysm Aortic Aneurysm Arrhythmia Arterial thromboembolism Atherosclerosis Cardiac septum problem Cerebral Hemorrhage/Stroke Heart valve disease Hemorrhage Hypertension Hypotension Ischemia Ischemic gut Ischemic heart disease Myocardial Infarction Pulmonary embolism Pulmonary hypertension Vasculitis Venous thromboembolism	Hereditary/congenital
Eye	Mechanism Transportation mechanism	Neoplastic Benign neoplasm Endocrine neoplasm Female genital neoplasm Gastrointestinal neoplasm Heme/immunology neoplasm Leukemia Lymphoma Male genital neoplasm Metastasis Musculoskeletal/soft tissue neoplasm Neuro neoplasm Primary malignancy Renal/Urinary neoplasm Respiratory neoplasm Skin neoplasm	Heme/immunology Allergy Anemia Heme/immunology neoplasm Hemophilia Leukemia Thrombocytopenia
Misc Adverse effect Alcohol related Allergy Anesthetic related Antidepressant related Awaiting/delayed transfer COVID Cannabis related Cocaine related Decubitus ulcer Diagnosis implying death Exposure Fistula Hallucinogen related Has one Healthcare contact Hemorrhage Iatrogenic Metabolic/nutrition Non-traumatic fracture Observation Organ removal Ostomy Overdose Paralysis Past medical history Poisoning Psychoactive substance NOS related Radiation related Retired Code Rheumatic disease Sedative related Shock Solvent related Spine Stimulant related Transplant	Reproductive Abortion Breast disease Female genital neoplasm Male genital neoplasm Peripartum	Gastrointestinal Cirrhosis GI ulcer Gastroenteritis Gastrointestinal neoplasm Hepatitis Hernia Inflammatory Bowel Disease Intra-abdominal infection Ischemic gut Liver disease Liver failure Pancreas disease Pancreatitis Peptic ulcer	Musculoskeletal/soft tissue Hernia Joint/ligament trauma Muscle problem Muscles/tendon trauma Musculoskeletal/soft tissue neoplasm Osteomyelitis
Psych Addiction Antidepressant related Delirium Dementia Hallucinogen related Opioid related Psychoactive substance NOS related Sedative related Solvent related Stimulant related Withdrawal	Respiratory Asthma Influenza Inhalation Lower respiratory tract infection Pleural abnormalities Pneumoconiosis Pneumonia Pneumothorax Pulmonary embolism Respiratory neoplasm Sleep disorder Tracheostomy Upper respiratory tract infection	Poisoning Acute intoxication Addiction Opioid related Overdose Poisoning by non-pharmaceuticals Stimulant related Withdrawal
Neuro Cerebral Hemorrhage/Stroke Encephalitis Encephalopathy Meningitis Neuro neoplasm Paralysis	Symptom/Sign Pain	Endocrine disorder Adrenal Insufficiency Diabetes Endocrine neoplasm Metabolic/nutrition

Show all ICD10 Subcategories

ICD10 Categories: ANCA-associated Vasculitis (AAV), Abdominal trauma, Abortion, Acute intoxication, Addiction, Adrenal Insufficiency, Adverse effect, Alcohol related, Allergy, Anemia, Anesthetic related, Aneurysm, Antibiotic resistance, Antidepressant related, Aortic Aneurysm, Arrhythmia, Arterial thromboembolism, Asthma, Atherosclerosis, Awaiting/delayed transfer, Bacteria, Benign neoplasm, Breast disease, Burn, COVID, Cannabis related, Cardiac septum problem, Cardiovascular, Cerebral Hemorrhage/Stroke, Chemical burn, Chronic kidney disease, Cirrhosis, Cocaine related, Decubitus ulcer, Delirium, Dementia, Diabetes, Diagnosis implying death, Double duty pathogen, ENT, Encephalitis, Encephalopathy, Endocrine disorder, Endocrine neoplasm, Exposure, Eye, Female genital neoplasm, Fistula, Fracture, Fungus, GI ulcer, Gastroenteritis, Gastrointestinal, Gastrointestinal neoplasm, Hallucinogen related, Has one, Head trauma, Head trauma (old), Healthcare contact, Heart valve disease, Heme/immunology, Heme/immunology neoplasm, Hemophilia, Hemorrhage, Hepatitis, Hereditary/congenital, Hernia, Hypertension, Hypotension, Iatrogenic, Iatrogenic infection, Iatrogenic mechanism, Imaging, Infection requiring pathogen, Infection with implied pathogen, Infectious disease, Inflammatory Bowel Disease, Influenza, Inhalation, Intra-abdominal infection, Ischemia, Ischemic gut, Ischemic heart disease, Joint/ligament trauma, Leukemia, Liver disease, Liver failure, Lower limb trauma, Lower respiratory tract infection, Lymphoma, Male genital neoplasm, Mechanism, Meningitis, Metabolic/nutrition, Metastasis, Misc, Muscle problem, Muscles/tendon trauma, Musculoskeletal/soft tissue, Musculoskeletal/soft tissue neoplasm... further results